 Triclabendazole
|
||
PRODUCT TRICLABENDAZOLE |
SPECIFICATION OF TRICLABENDAZOLE |
||
S.NO |
TESTS |
SPECIFICATION |
| 1 | Description | Off-White to light brown coloured crystalline or amorphous powder. |
| 2 | Solubility | 0.2 grams sample is soluble in 25 ml absolute Ethanol |
| 3 | Identification | a) UV absorption spectrum exhibits maxima only at the same wavelengths as that of a similar preparation of triclabendazole reference standard. |
| b) The intensity of principle band obtained from test solution corresponds to that obtained from the standard solution by TLC. | ||
| 4 | Melting Range | About 170 Deg.C |
| 5 | Moisture Content | Not more than 1.0% |
| 6 | Sulphated Ash | 0.5% |
| 7 | Related Impurities HPLC | N-methyl derivative is NMT 1.5%, Total impurities NMT 2.0% |
| 8 | Assay By HPLC | It contain Not less than 98.0% and not more than 102.0% of C14H9CL3N2OS |